Interplay of ELF5, GATA-3 and FLI-1 regulate malignant transformation of keratinocytes.
2026-07-16 · 论文 · upload
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摘要
Cutaneous squamous cell carcinoma (cSCC) arises from epidermal keratinocytes and is the second most common epithelial malignancy. E74-like factor 5 (ELF5) is a member of the epithelium specific ETS subfamily of transcription factors and is essential for epithelial development, homeostasis and prevention of epithelial tumourigenesis.